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In addition, probiotics can stimulate the host’s antioxidant defence systems and increase the activity of antioxidant enzymes (224)

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The latest research indicates that I3A not only sustains lung epithelial barrier function through AhR receptor activation and IL-22 secretion stimulation but also inhibits HDAC5/6, resulting in the inactivation of the NF-κB/NLRP3 signaling pathway and the subsequent reduction of inflammatory factor expression (66)